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Course Material:
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Other Links:
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Course Outline
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- Introduction to Supramolecular Chemistry
- Inspiration
- History
- Definitions
- Molecular Forces
- covalent bonding
- ion - ion
- ion - dipole
- dipole - dipole
- hydrogen bonding
- cation - pi interactions
- pi - pi stacking
- van der Waals forces
- the hydrophobic effect / solvent effects / phase separation
- Molecular Structure: Shape and Size
- van der Waals radii
- bond lengths and bond angles
- conformation
- Common Motifs in Supramolecular Chemistry
- Brief Overview of Experimental Techniques in Supramolecular Chemisry
- NMR
- Electron Microscopy
- Scanning Probe Microscopy
- Host / Guest Chemistry
- Cation binding
- Anion binding
- Neutral molecule binding
- Peptides & Proteins, Assembly & Structure
- Examples
- Primary Structure
- amino acids
- back bone
- Secondary Structure
- alpha helix
- beta sheets
- other conformations
- Nucleic acid structure & molecular recognition
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