The course will be divided into three sections. Section 1 of this course will be a presentation of the basic laws of classical thermodynamics with illustrations of their biological application. At the end of section 1, an exam will be given that will gauge the level of understanding that has been achieved of the basics of thermodynamics.  Because thermodynamics is a heirarchial subject, it is necessary to have a firm understanding of the basics before moving onto advanced material.  

Section 1
 

Date	Lecture Topic	Reading Material	Homework Assignment	Exams
Jan. 11	Course Overview - History of Thermodynamics		HW #0, due Jan. 13
Jan. 13	Thermodynamic Systems, Properties and the Zeroth Law	Handout	HW #1, due Jan. 20
Jan. 16	NO CLASS - Martin Luther King, Jr. Day	Click Here
Jan. 18	Properties of Ideal and Real Gases	Chap. 2
Jan. 20	The First Law of Thermodynamics	Chap. 5	HW #2 due Jan. 27
Jan. 23	Enthalpy and Heat Capacity	Chap. 5
Jan. 25	Thermochemistry	Chap. 5
Jan. 27	The Second Law of Thermodynamics	Chap. 6	HW #3 due Feb. 4
Jan.  30	Heat Engines and  Isothermal Systems	Chap. 6
Feb. 1	Molecular Energy Levels	Chap. 1
Feb. 3	Boltzmann Factor	Chap. 3	HW #4 due Feb. 11
Feb. 6	Polymer Thermodynamics	Handout
Feb.  8	Lipids and Membranes	Handout
Feb.  10	Partition Functions	Chap. 3	HW #5 due Feb. 17
Feb.  13	Molecular Partition Functions	Chap. 3
Feb.  15	Partition Functions and Ideal Gases	Chap 4
Feb.  17	Molecular Interpration of First and Second Law	5-6,6-5,6-8
Feb. 20	No Class
Feb.  22	No Class
Feb.  23/24	Exam 1	Chapters 1-6
Feb. 27	Membrane Phases

Section 2 will include lectures focused on the Gibbs Free Energy, chemical potential and inerfacial thermodynamics.  The electrochemical potential will also be developed and its application to membrane transport will be discussed in detail.  The thermodynamics of membrane carriers, pumps, symporters and antiporters will be developed.

Section 2
 

Mar.  1	The Third Law - Entropy and Reversible Processes	Chap 7
Mar. 3	The Third Law - Entropy and Reversible Processes	Chap 7	HW #5 due March 19
Mar. 12	Helmholtz and Gibbs Free Energy and Chemical Potential	Chap 8
Mar. 15	Helmholtz and Gibbs Free Energy and Chemical Potential	Chap 8
Mar.  17	Helmholtz and Gibbs Free Energy and Chemical Potential	Chap 8
Mar. 19	Phase Equilibria	Chap 9	HW #6 due March 26
Mar. 22	Clapeyron Equation	Chap 9
Mar. 24	Chemical Potential and the Partition Function	Chap 9
Mar.  26	Liquid-Liquid Solutions	Chap 10
Mar.  29	Partial Molar Quanties and Gibbs-Duhem Relation	Chap 10	HW #7 due April 2nd
Mar.  31	Activity	Chap 10
Apr. 2	NonIdeal Mixtures	Chap 10
Apr. 5	Solid-Liquid Solutions	Chap 11	HW#8  due April  9th
April 7	Solid-Liquid Solutions	Chap 11
April 9	Chemical Equilibrium	Chap 12
April 12	Chemical Equilibrium	Chap 12	Exam 2 this week Chapters 7-10
April 14	Chemical Equilibrium	Chap 12

 

Section 3 will introduce statisical thermodynamics, nonequilibrium thermodynamics and other advanced topics in biological thermodynamics.  The power of applying thermodynamics to membranes, polymers, liquid crystals, nanoscale devices, the thermodynamics of DNA and evolution will be treated.  The final topics treated will include: information theory, complexity and evolution.

Section 3
 

Apr. 16	No Class
Apr. 19	Thermodynamics of Cell Adhesion Thermodynamics of Electromechanical Coupling
Apr.  21	Thermodynamics of Protein Folding
Apr. 23	The Closing	Chap 14
Apr.  ?				The Final